- Prepare the Ingredients

Preheat oven to 375°F. In a small bowl, combine the breadcrumbs and milk; set aside to soak for 5 minutes. In a separate small bowl, whisk together all the glaze ingredients: ketchup, brown sugar, and apple cider vinegar. Finely dice the onion and mince the garlic.
- Combine the Meat Mixture
In a large mixing bowl, gently combine the ground beef, soaked breadcrumb mixture, diced onion, minced garlic, eggs, mayonnaise, Worcestershire sauce, Dijon mustard, thyme, salt, and pepper. Use your hands to mix just until all ingredients are evenly distributed and no dry pockets remain. Be careful not to overmix.
- Shape and Bake
Transfer the meat mixture to a rimmed baking sheet lined with parchment paper. Shape it into a 9x5-inch loaf, mounding it slightly in the center. Place in the preheated oven and bake for 40 minutes.
- Glaze and Finish

After 40 minutes, remove the loaf from the oven. Spoon or brush about half of the prepared glaze evenly over the top and sides. Return to the oven and bake for an additional 20-25 minutes, or until the internal temperature reaches 160°F. Remove and let rest for 10 minutes before slicing. Serve with the remaining glaze on the side.
- Calories:420 kcal
- Protein:32 g
- Carbohydrates:22 g
- Sugar:12 g
- Salt:0.9 g
- Energy:1760 kJ
- Fat:23 g
Few dishes satisfy like a truly great meatloaf recipe. It’s not just dinner; it’s a warm hug in food form, evoking the comforting crackle of a vinyl seat at a family diner. The key is a moist, tender crumb and that legendary sweet-and-savory glaze that caramelizes into a sticky crust. My quest for the perfect version led me to a simple, surprising trick, and I’m thrilled to share it. This isn’t just any meatloaf recipe—it’s the one you’ll keep coming back to.
The Legend of the Meatloaf Recipe
This humble American classic has a knack for morphing. Its roots twist from ancient Roman patties to German ‘Hackbraten,’ landing on Depression-era dinner tables as a thrifty way to stretch a single pound of meat. It’s a dish of resourcefulness, which is why, to this day, the best meatloaf recipe is a blank canvas for your pantry. I love that about it.
Why This Recipe Works
The magic here is twofold. First, texture. Using milk-soaked breadcrumbs (a ‘panade’) creates an emulsion that guarantees a succulent, never-dry loaf. Second, the flavor secret: a good dollop of mayonnaise. It sounds odd, but trust me. It adds a subtle tang, incredible moisture, and helps the meat mixture hold together perfectly. The result is a rich, savory, ground beef meatloaf with a crumb so tender it practically melts.
The Non-Negotiable Pro-Tip
Do not overmix. Once you combine your wet and dry ingredients with the meat, mix gently with your hands just until everything is incorporated. Overworking it will activate the proteins in the meat, making the final loaf tough and dense. Think of it as bringing the ingredients together for a team huddle, not a wrestling match.
Serving & Pairing Ideas
Slice your creation while it’s warm, letting the steam rise with that glorious aroma. It’s divine with classic mashed potatoes and a side of green beans. But for a twist, try it with a bright, vinegary coleslaw for crunch or roasted Brussels sprouts. A dark ale or a robust Zinfandel cuts beautifully through the richness. Leftovers, cold in a sandwich on toasted rye with a smear of mustard? Unbeatable.
Variations & Substitutions
This is a wonderfully adaptable dish. For a lighter, poultry-based version, swap half the beef for ground turkey. Gluten-free? Use rolled oats instead of breadcrumbs. Want to sneak in veggies? Grated zucchini or finely chopped mushrooms work wonders (just squeeze out excess moisture first). If you’re on the hunt for the best meatloaf recipe for a crowd, this base is incredibly forgiving—double it and bake it in a sheet pan for easy slices.
Make-Ahead & Storage Wisdom
You can assemble the loaf a day ahead, cover tightly, and refrigerate until ready to bake—it might need an extra 5-10 minutes in the oven. Cooked leftovers keep well in the fridge for 3-4 days. To freeze, wrap individual slices tightly; they reheat beautifully in a low oven or toaster oven. For more brilliant food science tips, check out the experts at Serious Eats.
Frequently Asked Questions
Q: Can I use a different ground meat?
A: Absolutely! A mix of ground beef and pork (or veal) is classic. For a straight-up ground beef meatloaf, an 85/15 blend offers great flavor without being too greasy.
Q: Why is my loaf falling apart?
A: It likely needs more binder or was sliced too hot. Ensure your panade is properly mixed in, and let the loaf rest for 10-15 minutes after baking. This lets the proteins relax and reabsorb juices, setting the structure.
There you have it. The comforting, reliable, endlessly tweakable masterpiece that is a great meatloaf. This recipe is a starting point for your own kitchen legend. So, roll up your sleeves, get your hands in the bowl, and create something wonderful. I’d love to hear how yours turns out!
















